Disclaimer: This article is for educational purposes only. Enclomiphene is sold strictly for research purposes only and is not approved for human consumption.
Introduction
One of the most common questions in the world of hormonal recovery research is: “How much can Enclomiphene actually raise testosterone?”
While several compounds have been studied for post-cycle therapy (PCT) or hormone restoration, Enclomiphene has emerged as one of the most promising options in 2025. Unlike older SERMs such as Clomid, Enclomiphene provides targeted action, impressive testosterone increases, and a cleaner side-effect profile.
Let’s take a closer look at what the published research shows, why testosterone increases with Enclomiphene can be so significant, and why it is increasingly viewed as the modern gold standard in PCT research.
A Quick Recap: How Enclomiphene Works
Enclomiphene is one of two isomers that make up Clomiphene citrate (Clomid). Unlike zuclomiphene — the isomer associated with estrogenic activity and side effects — Enclomiphene is the active isomer that drives testosterone recovery.
It works by stimulating the hypothalamus to increase secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These signals then prompt the testes to resume natural testosterone production.
What makes Enclomiphene unique is its selectivity. By isolating the “useful half” of Clomid, researchers are able to study testosterone restoration without the baggage of unnecessary estrogenic interference.
What Research Shows About Testosterone Increases Phase II and III Clinical Trials
Several clinical studies have directly measured testosterone increases with Enclomiphene:
In men with secondary hypogonadism, Enclomiphene consistently restored testosterone to the normal or mid-normal range.
Average increases of 200–300 ng/dL were observed, with some men moving from clinically low levels (~200 ng/dL) back to healthy ranges (~500 ng/dL or more).
LH and FSH also rose significantly, showing that Enclomiphene was not just masking symptoms but reactivating the body’s own hormonal axis.
Head-to-Head vs Clomid
When compared with Clomid, Enclomiphene often demonstrated equivalent or superior testosterone increases, but with fewer side effects such as mood swings, visual disturbances, or estrogen rebound.
This is because Enclomiphene delivers the desired androgenic benefits without zuclomiphene, which lingers in the body and drives many of Clomid’s drawbacks.
Consistency Across Studies
What stands out most is the reliability of Enclomiphene’s effect. Multiple trials have shown:
Testosterone restoration within weeks.
Sustained increases over the duration of studies.
Predictable improvements in both testosterone and gonadotropins (LH, FSH).
Why These Increases Matter in PCT Research
In research involving SARMs or anabolic steroids, natural testosterone production is often suppressed. Left unsupported, recovery can be slow and inconsistent, leading to prolonged low testosterone.
Enclomiphene offers a solution by:
Speeding up recovery: Testosterone levels return to normal ranges more quickly.
Supporting retention: Higher testosterone means less muscle loss and faster recovery of strength.
Protecting wellbeing: Normalised testosterone is linked with improved mood, energy, libido, and sleep quality.
In short, the testosterone increases observed in research aren’t just numbers on a blood test — they translate into meaningful recovery outcomes.
Enclomiphene vs Other Options
Clomid (Clomiphene citrate)
Raises testosterone, but side effects are more common.
Estrogenic activity of zuclomiphene can cause mood instability and visual disturbances.
Less targeted compared to Enclomiphene.
Testosterone Replacement Therapy (TRT)
Provides exogenous testosterone but further suppresses natural production.
Useful for long-term management, but not ideal for recovery studies where the goal is natural restoration.
Natural Recovery Alone
Can take months or longer, with inconsistent results.
Risk of prolonged low testosterone symptoms.
Against these alternatives, Enclomiphene stands out as more targeted than Clomid, more restorative than TRT, and more effective than doing nothing.
Read Next: Enclomiphene vs Clomid: Key Differences in Research
Additional Benefits Observed in Research
While the headline finding is testosterone increases of 200–300 ng/dL, Enclomiphene has also been associated with:
Improved sperm counts in fertility research.
Balanced estrogen levels without rebound spikes.
Improved body composition markers, likely a downstream effect of restored testosterone.
These findings highlight Enclomiphene’s potential as a comprehensive hormonal recovery tool in research settings.
Factors That Influence Testosterone Increases
Not every research subject responds identically, but several factors can influence how much Enclomiphene raises testosterone:
Baseline levels: Lower starting testosterone tends to produce bigger jumps.
Age: Younger men may recover more robustly, but older men have also shown strong responses in clinical trials.
Duration of suppression: Longer or harsher suppression may require more time for recovery.
Lifestyle variables: Adequate sleep, diet, and training all support Enclomiphene’s effectiveness.
Why Researchers Are Excited About Enclomiphene
Enclomiphene offers a rare combination of qualities:
Strong testosterone increases documented in multiple trials.
Selective, targeted mechanism with minimal off-target activity.
Cleaner safety profile compared to older SERMs.
Consistent results, making it easier for researchers to track outcomes.
In many ways, Enclomiphene is becoming recognised as the modern standard for testosterone restoration research.
Where to Source Research-Grade Enclomiphene
For researchers seeking high-quality compounds, Affordable Nutrition provides lab-tested Enclomiphene capsules, dispatched quickly within the UK.
All products are intended strictly for research purposes only and are not approved for human consumption.
Conclusion
So, how much does Enclomiphene raise testosterone? Current research suggests increases of 200–300 ng/dL on average, often restoring men from low to healthy ranges within weeks.
Compared to older options like Clomid, Enclomiphene delivers the same or greater testosterone restoration with fewer side effects and more targeted action. Against TRT or natural recovery, it provides a faster, more sustainable return to normal hormonal balance.
For researchers in 2025, Enclomiphene isn’t just another SERM — it is fast becoming the preferred option for investigating testosterone recovery thanks to its reliability, effectiveness, and modern design.
For more information why not have a read of What Is Enclomiphene? A Beginner’s Guide to Boosting Testosterone