MK677 and LGD4033 – 60 Capsules

High-Purity MK-677 & LGD-4033 – 60 Dual-Compound Capsules

MK-677 (Ibutamoren) and LGD-4033 (Ligandrol) are two investigational compounds studied for their distinct roles in growth hormone regulation, androgen-receptor signalling and skeletal muscle research.

This dual-compound formulation contains 10mg of MK-677 and 4.5mg of LGD-4033 per capsule, bringing together two different research compounds in one clearly specified formulation.

Although frequently discussed within the same broader research field, the compounds act through different biological pathways. MK-677 is a growth hormone secretagogue, whereas LGD-4033 is a non-steroidal Selective Androgen Receptor Modulator (SARM).

MK-677 & LGD-4033 in Research

The two compounds have attracted scientific interest for their separate mechanisms and biological activities.

MK-677 (Ibutamoren)

MK-677 is a growth hormone secretagogue that interacts with the ghrelin receptor, also known as the growth hormone secretagogue receptor (GHSR).

Controlled human research has investigated its influence on growth hormone (GH), insulin-like growth factor 1 (IGF-1) and several physiological markers.

Research involving MK-677 has examined:

• Growth hormone and IGF-1 regulation

• Lean body mass and body-composition markers

• Sleep-related hormonal activity

• Age-related endocrine changes

• Bone and connective-tissue metabolism

• Glucose regulation and metabolic responses

LGD-4033 (Ligandrol)

LGD-4033, commonly known as Ligandrol, is a non-steroidal SARM investigated for its interaction with androgen receptors in muscle, bone and other androgen-responsive tissues.

Published human clinical research has examined its effects on lean body mass, hormonal markers and pharmacokinetic characteristics.

Research involving LGD-4033 has examined:

• Lean body mass and skeletal muscle biology

• Androgen-receptor binding and activation

• Tissue-selective androgen signalling

• Muscle strength and physical function markers

• Bone metabolism and androgen-responsive tissues

• Testosterone, SHBG and endocrine regulation

Understanding the Two Research Mechanisms

MK-677 and LGD-4033 act through different receptor systems:

• MK-677 interacts with the ghrelin receptor and influences growth hormone and IGF-1 signalling

• LGD-4033 interacts with androgen receptors involved in muscle, bone and endocrine regulation

These distinct mechanisms provide useful context when examining the compounds within the same formulation.

However, published research into the individual compounds does not establish additional benefits, safety or effectiveness when they are combined.

For further scientific context, published human research examining MK-677 (Ibutamoren) and LGD-4033 (Ligandrol) is available through PubMed.

Why Choose Affordable Nutrition UK MK-677 & LGD-4033?

• Two investigational compounds supplied in one clearly specified capsule formulation

• Each capsule contains 10mg MK-677 and 4.5mg LGD-4033

• Third-party analytical testing reporting over 99% purity for the tested compounds

• Excellent value at only £47.95 for 60 capsules, with multi-buy savings available

• Manufactured in a UK ISO 9001-certified facility under GMP quality controls rather than sourced as generic ready-made imported capsules

• Certificates of Analysis available directly in the Data Sheets section

• Established UK business trusted by over 30,000 customers nationwide

Shipping & Packaging

• UK-based same-day dispatch on orders placed before 4pm Monday–Friday

• Rapid tracked UK delivery using Royal Mail Tracked 24

• Discreet plain packaging with no external product identification

• Free standard delivery on orders of £75 or more

Independent Testing & Quality

For research compounds, label claims alone are not enough.

Affordable Nutrition UK prioritises product identity, independent analytical testing and transparency. Our MK-677 & LGD-4033 product is independently tested by MZ Biolabs, a specialist analytical laboratory with extensive experience in research compounds.

The current Certificate of Analysis is available through the Data Sheets tab above, featuring QR-code verification linking directly to the laboratory-hosted certificate on MZ Biolabs’ website.

Learn more about our commitment to independently verifiable testing, Certificates of Analysis and product quality on our Testing & Quality page.